Ketorolac Ophthalmic

What is ketorolac?

Ketorolac (brand names: Acular®, Acular LS®, Acuvail®) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammation in the eye and to control pain after cataract surgery.

Its use in cats, dogs, or other pets to treat pain and inflammation is “off label” or “extra-label”. Many drugs are commonly prescribed for off-label use in veterinary medicine. In these instances, follow your veterinarian’s directions and cautions very carefully, as they may be significantly different from those on the label.

How is ketorolac given?

• Ketorolac is given in the form of a liquid drop applied directly to the eye. 
• Wash your hands before administering this medication. 
• Do not touch the tip of the dropper to the surface of the eye or any other surface. 
• Give this medication at least 5 minutes apart from other medications used in the eye. 
• Wipe off excess medication on the face with a damp cloth or tissue. 
• Do not give this to your pet if the medication is cloudy or changes color.

This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.

What if I miss giving my pet the medication?

If you miss a dose, give it when you remember. However, if it is close to the time for the next dose, skip the dose you missed, give it at the next scheduled time, and return to the regular dosing schedule. Never give your pet 2 doses at once or give extra doses.

Are there any potential side effects?

The most common side effects include: 

• temporary stinging sensation upon application
• mild redness

SERIOUS ADVERSE REACTIONS associated with this medication may occur without warning. If any of the following signs develop, stop giving ketorolac and contact your veterinarian immediately:

• facial swelling
• difficulty breathing
• skin rash
• bleeding in the eye
• sensitivity to bright light

This moderate-acting medication should stop working in a few days.

Are there any risk factors for this medication?

Ketorolac SHOULD NOT BE USED in pets that are allergic to it. It should be used cautiously in pets that:

• are allergic to aspirin or other NSAIDs
• are pregnant or nursing
• have asthma
• have dry eye syndrome
• have corneal ulcers
• have bleeding disorders

Are there any drug interactions I should be aware of?

There are no specific drug interactions with ketorolac ophthalmic. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking.

Is any monitoring needed with this medication?

No specific monitoring is needed while your pet is taking this medication. Your veterinarian may monitor your pet to be sure that the medication is working. Monitor your pet at home for serious side effects.

How do I store ketorolac?

• Store at a controlled room temperature between 59°F and 77°F (15°C and 25°C). Protect from moisture, sunlight, and freezing.
• Keep the container tightly sealed when not using it.
• Store compounded forms of this medication according to the label.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.