Library
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This handout outlines the use of disease-modifying osteoarthritis drugs (DMOADs) in cats, specifically the use of polysulfated glycosaminoglycans (PSGAGs). The rationale for their use, potential side effects, and treatment expectations are explained.
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Kaolin/pectin is given by mouth and is used off label to treat diarrhea and certain toxicities. Use as directed by your veterinarian. Side effects are uncommon, but constipation is possible (rarely). Do not use in pets that are allergic to it, or to control severe diarrhea or diarrhea that is caused by an infection. Do not use the combination product that includes bismuth subsalicylate in cats. If a negative reaction occurs, please call your veterinary office.
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Ketoconazole is an antifungal given by mouth in the form of a tablet, used off label to treat fungal infections in dogs, cats, small mammals, and reptiles. The most common side effects are vomiting, diarrhea, lack of appetite, and weight loss. Do not use in pets that are allergic to it and use extreme caution when using in cats or pregnant pets.
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Ketoconazole otic is an antifungal used in the treatment of external ear infections (otitis externa) caused by yeast in cats, dogs, and other animals. Ketoconazole otic comes in ointment or liquid drop suspension forms that may be specially compounded and/or combined into a formulation with other medications.
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Ketoconazole topical is an antifungal used in the treatment of skin infections caused by fungal organisms in cats, dogs, and other animals. It comes in a variety of forms that may be specially compounded and/or be combined with other medications.
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Ketoprofen is given by mouth in the form of a capsule or tablet to treat pain and inflammation in dogs and horses. It’s use in animals is off label. Do not use this medication in pets that are allergic to it, or in pets concurrently using corticosteroids or other NSAIDs. If a negative reaction occurs, call your veterinary office.
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Ketorolac is applied topically to the eye to treat pain and inflammation of the eye. Its use in dogs and cats is off label. Do not use this medication in pets that are allergic to it. If a negative reaction occurs, call your veterinary office.
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Lactated Ringer’s solution (also known as LRS, Ringer’s Lactate) is a fluid and electrolyte (salts) replacement solution used to correct fluid and electrolyte imbalances in cats, dogs, birds, pocket pets (small mammals), and other animals. Lactated Ringer’s solution comes in injectable form, usually given subcutaneously for at home administration.
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Lactulose is used off label and is given by mouth to treat high blood ammonia levels and constipation in dogs, cats, birds, and reptiles. The most common side effects are diarrhea, bloating, gas, and abdominal cramping. Do not use in pets that are allergic to it or in pets with intestinal blockage/obstruction.
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Latanoprost ophthalmic is applied in the eye and is used off label to treat elevated eye pressures and glaucoma. Give as directed by your veterinarian. Side effects include a burning or stinging sensation, mild eye redness, growth of eyelashes, or color change of the iris or around the eye. Do not use in pets that are allergic to it, or with eye inflammation (uveitis). If a negative reaction occurs, please call your veterinary office.
